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Diphenyleneiodonium chloride

SKU T7191-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 61 CAD through 549 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7191

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C12H8ClI

Citations

– 1. Li J, Chen S, Huang J, et al. New Target in an Old Enemy: Herbicide (R)-Dichlorprop Induces Ferroptosis-like Death in Plants. Journal of Agricultural and Food Chemistry. 2021 2. Tao L, Liu Z, Li X, et al.Oleanonic acid ameliorates mutant Aβ precursor protein-induced oxidative stress, autophagy deficits, ferroptosis, mitochondrial damage, and ER stress in vitro.Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease.2024: 167459. 3. Ning Y, Chen Y, Tian T, et al.S100A7 Orchestrates Neutrophil Chemotaxis and Drives Neutrophil Extracellular Traps (NETs) Formation to Facilitate Lymph Node Metastasis in Cervical Cancer Patients.Cancer Letters.2024: 217288.

References

– Singh A K , Thakare R , Karaulia P , et al. Biological evaluation of diphenyleneiodonium chloride (DPIC) as a potential drug candidate for treatment of non-tuberculous mycobacterial infections[J]. Journal of Antimicrobial Chemotherapy, 2017.

CAS Number

– 4673-26-1

Molecular Weight

– C12H8ClI

Compound Purity

– 0.9971

SMILES

– [Cl-].[I+]1c2ccccc2-c2ccccc12

Pathway

– Membrane transporter/Ion channel|||NF-κB|||Immunology/Inflammation|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.