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Dihydromyricetin

SKU T2998-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 62 CAD through 554 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy by inhibiting mTOR signaling.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2998

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H12O8

Citations

– 1. Xiao T, Wei Y, Cui M, et al. Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis. Phytomedicine. 2021: 153704. 2. Liu H, Ye F, Sun Q, et al. Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro. Journal of Enzyme Inhibition and Medicinal Chemistry. 2021, 36(1): 497-503 3. Li J, Xiao X, Ou Y, et al.USP51/PD‐L1/ITGB1‐deployed juxtacrine interaction plays a cell‐intrinsic role in promoting chemoresistant phenotypes in non‐small cell lung cancer.Cancer Communications.2023 4. He H, Huang Y, Zhang X, et al.Supercritical fluid coating of flavonoids on excipients enhances drug release and antioxidant activity.International Journal of Pharmaceutics.2023: 122593.

References

– Zhang YS, et al. Yao Xue Xue Bao, 2003, 38(4), 241-244.

CAS Number

– 27200-12-0

Molecular Weight

– C15H12O8

Compound Purity

– 0.9813

SMILES

– O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1cc(O)c(O)c(O)c1

Pathway

– Cell Cycle/Checkpoint|||Autophagy|||Microbiology/Virology|||DNA Damage/DNA Repair|||Membrane transporter/Ion channel|||Neuroscience|||PI3K/Akt/mTOR signaling

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.