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Dihydroartemisinin

SKU T0607-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 53 CAD through 80 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

20 mg 1 mL * 10 mM (in DMSO)

Clear

Products Details

Product Description

– Dihydroartemisinin (Artenimol) is a metabolite of artemisinin.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T0607

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H24O5

Citations

– 1. Liu W, Zheng M, Zhang R, et al.RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy.Advanced Science.2022: 2203884. 2. Wang J, Zhang J, Guo Z, et al.Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.Phytomedicine.2023: 155156. 3. Hsu Y F, Kung F L, Huang T E, et al.Anticancer Activity and Molecular Mechanisms of an Ursodeoxycholic Acid Methyl Ester-Dihydroartemisinin Hybrid via a Triazole Linkage in Hepatocellular Carcinoma Cells.Molecules.2023, 28(5): 2358. 4. Liu Y, Li H, Luo Z, et al. Artesunate, a new antimalarial clinical drug, exhibits potent anti‐AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways. British Journal of Pharmacology. 2022 5. Md. Yusuf N, Azman A N, Abdul Aziz A A, et al.Evaluation of the binding interactions between Plasmodium falciparum Kelch-13 mutant recombinant proteins with artemisinin.PloS one.2024, 19(8): e0306975.

References

– Aung W, et al. Anticancer Res. 2011, 31(5):1549-1558.

CAS Number

– 71939-50-9

Molecular Weight

– C15H24O5

Compound Purity

– 0.9972

SMILES

– C[C@@H]1[C@]2([C@]34[C@@](O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])(O[C@@H]1O)[H])[H]

Target

– Dehydrogenase

Pathway

– Microbiology/Virology|||Apoptosis|||Autophagy|||NF-κB

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.