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Digitonin

SKU T2721-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 46 CAD through 48 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)25 mg

Clear

Products Details

Product Description

– Digitonin is a natural product of the glycoside family and is a detergent. Digitonin has antitumor activity, binds to cholesterol molecules to increase the permeability of cell membranes, and is active in the cleavage of cell membranes in a wide range of cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2721

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C56H92O29

Citations

– 1. Chen Y, Wang X, Shi H, et al. Montelukast Inhibits HCoV-OC43 Infection as a Viral Inactivator. Viruses. 2022, 14(5): 861 2. He Z, Zhang Z, Xu P, et al.Laminarin Reduces Cholesterol Uptake and NPC1L1 Protein Expression in High-Fat Diet (HFD)-Fed Mice.Marine Drugs.2023, 21(12): 624. 3. Wang Z, Cui L, Lin Y, et al.Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity.The EMBO Journal.2024: 1-18.

References

– Schäfer T, et al. Digitonin-permeabilized cells are exocytosis competent. J Neurochem. 1987 Dec;49(6):1697-707.

CAS Number

– 11024-24-1

Molecular Weight

– C56H92O29

Compound Purity

– 0.5

SMILES

– [H][C@@]12O[C@]3(CC[C@@H](C)CO3)[C@@H](C)[C@]1([H])[C@@]1(C)CC[C@@]3([H])[C@@]([H])(CC[C@@]4([H])C[C@@H](O[C@]5([H])O[C@H](CO)[C@H](O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O[C@]7([H])OC[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@]6([H])O[C@H](CO)[C@H](O)[C@H](O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)C[C@]34C)[C@]1([H])[C@@H]2O

Pathway

– Others

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.