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Desmorpholinyl Navitoclax-NH-Me

SKU T39910-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 104 CAD through 1,744 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T39910

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C44H51ClF3N5O5S3

References

– Guangrong Zheng, et al. Agents de dégradation de protéines bcl-2 pour le traitement du cancer. WO2019144117A1.

CAS Number

– 2365172-82-1

Molecular Weight

– C44H51ClF3N5O5S3

Compound Purity

– 0.9987

SMILES

– CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1

Pathway

– Apoptosis

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.