Desmorpholinyl Navitoclax-NH-Me

SKU T39910-1 mL * 10 mM (in DMSO) Category PROTAC Brand: TargetMol

Price range: 104 CAD through 1,744 CAD

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Product Description

– Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].

Web ID

– T39910

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C44H51ClF3N5O5S3

References

– Guangrong Zheng, et al. Agents de dégradation de protéines bcl-2 pour le traitement du cancer. WO2019144117A1.

CAS Number

– 2365172-82-1

Molecular Weight

– C44H51ClF3N5O5S3

Compound Purity

– 0.9987

SMILES

– CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1

Pathway

– Apoptosis

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Desmorpholinyl Navitoclax-NH-Me

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