Demethylzeylasteral

SKU T3418-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 315 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities. It inhibits the invasion of triple-negative breast cancer by blocking the TGF-β signaling pathway, and it can significantly reduce atherosclerosis.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T3418

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H36O6

Citations

– 1. Yang D L, Zhang Y, He L, et al. Demethylzeylasteral (T-96) Initiates Extrinsic Apoptosis Against Prostate Cancer cells by Inducing ROS-Mediated ER Stress and Suppressing Autophagic Flux. Biological Research. 2021, 54(1): 1-14. 2. Yang Y, Zhao M, Hu T, et al. Identification of an antitumor effect of demethylzeylasteral on human gastric cancer cells. Oncology Letters. 2021, 21(1): 1-1.

References

– Liu SL et al. Eur J Drug Metab Pharmacokinet. 2014 Jun;39(2):99-102.

CAS Number

– 107316-88-1

Molecular Weight

– C29H36O6

Compound Purity

– 0.9954

SMILES

– [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC(=O)c4c(C=O)c(O)c(O)cc4[C@]3(C)CC[C@@]21C)C(O)=O

Target

– Antioxidant

Pathway

– Apoptosis|||Metabolism

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.