Cyclotraxin B

Name: Cyclotraxin B | TRKB Agonist — Buy Online | Immunomart
Brand: TargetMol
SKU: TP2068-1 mg

SKU TP2068-1 mg Category Peptide Brand: TargetMol

Products Details

Product Description

– Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM). Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TP2068

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C48H73N13O17S3

References

– Constandil et al (2012) Cyclotraxin-B, a new TrkB antagonist, and glial blockade by propentofylline, equally prevent and reverse cold allodynia induced by BDNF or partial infraorbital nerve constriction in mice. J.Pain 13 579 PMID:

CAS Number

– 1203586-72-4

Molecular Weight

– C48H73N13O17S3

SMILES

– O=C1N2[C@](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC3=CC=C(O)C=C3)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@H](C(O)=O)CSSC[C@H](N)C(=O)N[C@H]1CC(N)=O)[H])(CCC2)[H]

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.