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CYC-116
Price range: 53 CAD through 1,528 CAD
Products Details
Product Description
– CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.
Web ID
– T6458
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H20N6OS
References
– Wang S, et al. J Med Chem. 2010, 53(11), 4367-4378.
CAS Number
– 693228-63-6
Molecular Weight
– C18H20N6OS
Compound Purity
– 0.9759
SMILES
– Cc1nc(N)sc1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
Pathway
– Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||MAPK|||Angiogenesis|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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