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Cucurbitacin I

SKU TQ0196-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 123 CAD through 941 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Cucurbitacin I (JSI-124), a natural compound, is a selective inhibitor of JAK2/STAT3 with anti-cancer activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TQ0196

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H42O7

Citations

– 1. Gong X, Liu Y, Liang K, et al.Cucurbitacin I Reverses Tumor-Associated Macrophage Polarization to Affect Cancer Cell Metastasis.International Journal of Molecular Sciences.2023, 24(21): 15920.

References

– Song J, et al. Cucurbitacin I inhibits cell migration and invasion and enhances chemosensitivity in colon cancer. Oncol Rep. 2015 Apr;33(4):1867-71.

CAS Number

– 2222-07-3

Molecular Weight

– C30H42O7

Compound Purity

– 0.982

SMILES

– [H][C@@]12CC=C3[C@@]([H])(C=C(O)C(=O)C3(C)C)[C@]1(C)C(=O)C[C@]1(C)[C@H]([C@H](O)C[C@@]21C)[C@@](C)(O)C(=O)C=CC(C)(C)O

Pathway

– Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis|||Stem Cells

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.