CP-547632

SKU T10870L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 408 CAD

Products Details

Product Description

– CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRβ and related tyrosine kinases (TKs). PDGFRβ and related tyrosine kinases (TKs) CP-547632 has antitumour activity.

Web ID

– T10870L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H24BrF2N5O3S

References

– Beebe JS, et al. Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy. Cancer Res. 2003 Nov 1 ; 63(21):7301-9.

CAS Number

– 252003-65-9

Molecular Weight

– C20H24BrF2N5O3S

Compound Purity

– 0.9851

SMILES

– NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F

Target

– Vitamin

Pathway

– Tyrosine Kinase/Adaptors|||Angiogenesis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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