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Corynoxine B

SKU TQ0258-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 149 CAD through 405 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)5 mg

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Products Details

Product Description

– Corynoxine B (Cory B), a natural alkaloid isolated from Uncaria rhynchophylla (Miq. ), is an autophagy inducer that enhances the activity of Beclin 1/VPS34 complex and increases autophagy by facilitating the interaction between Beclin 1 and HMGB1/2, which may ameliorate Alzheimer’s disease. NVP-BAG956 (NVP-BAG956)

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– TQ0258

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H28N2O4

References

– Song JX, et al. HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B. Autophagy. 2014 Jan;10(1):144-54.

CAS Number

– 17391-18-3

Molecular Weight

– C22H28N2O4

Compound Purity

– 0.9972

SMILES

– O=C1[C@@]2([C@]3(N(CC2)C[C@@H](CC)[C@@H](C(C(OC)=O)=C/OC)C3)[H])C=4C(N1)=CC=CC4

Pathway

– Autophagy

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.