Compound SC-1

SKU T22424-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 1,525 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Compound SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. Compound SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular carcinoma cell lines[1].
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T22424

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H13ClF3N3O2

References

– Chun-Yu Liu, et al. Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells. Breast Cancer Res. 2013;15(4):R63.

CAS Number

– 1313019-65-6

Molecular Weight

– C21H13ClF3N3O2

Compound Purity

– 0.9941

SMILES

– FC(F)(F)C1=CC(NC(=O)NC2=CC=C(OC3=CC=C(C=C3)C#N)C=C2)=CC=C1Cl

Target

– Sodium Channel

Pathway

– Apoptosis|||JAK/STAT signaling|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.