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Complex 3
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Complex 3 is a fluorescent dithiocarbamate-copper complex exhibiting anticancer properties, specifically targeting mitochondria. It has excitation/emission maxima at 455-495/535 nm. Complex 3 inhibits the growth of pancreatic cancer cells BxPC-3, AsPC-1, PANC-1, and WI38, with IC50 values of 0.74, 0.41, 0.62, and 2.06 µM, respectively. In AsPC-1 cells, it induces lipid peroxidation, mitochondrial fragmentation and constriction, apoptosis, and cytokine-cytokine receptor interaction dysfunction. Furthermore, Complex 3 reduces tumor volume and induces apoptosis within tumors in AsPC-1 mouse xenograft models.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T205594
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H22Br3Cu3N8S4
CAS Number
– 2480150-28-3
Molecular Weight
– C26H22Br3Cu3N8S4
SMILES
– [Br-][Cu+]([N]=1C=CC=CC1C=2C=3C=CC=C[N]3[Cu+2]4([Br-])[S-]C(=N[N]24)SC)[N]=5C=CC=CC5C=6C=7C=CC=C[N]7[Cu+2]8([Br-])[S-]C(=N[N]68)SC
Target
– Others
Product type
– Dye-Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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