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Cl-amidine hydrochloride

SKU T10831L-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 59 CAD through 1,086 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Cl-amidine hydrochloride is an orally available PAD inhibitor that blocks histone 3 deimination and neutrophil extracellular trap formation and improves survival in septic mice. It induces apoptosis in cancer cells and induces miR-16 to cause cell cycle arrest.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T10831L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H20Cl2N4O2

Citations

– 1. Li B, Xu L, Wang Z, et al.Neutrophil Extracellular Traps Regulate Surgical Brain Injury by Activating the cGAS-STING Pathway.Cellular and Molecular Neurobiology.2024, 44(1): 36.

References

– Yuan Luo, et al. Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization. Biochemistry. 2006 Oct 3; 45(39): 11727–11736.

CAS Number

– 1373232-26-8

Molecular Weight

– C14H20Cl2N4O2

Compound Purity

– 0.9814

SMILES

– Cl.NC(=O)[C@H](CCCNC(=N)CCl)NC(=O)c1ccccc1

Target

– ADC Cytotoxin

Pathway

– Apoptosis|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.