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CI-1040

SKU T2443-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 77 CAD through 771 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2443

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H14ClF2IN2O2

Citations

– 1. Wu R, Pang S, Lv W, et al.Injectable pH‐Responsive CI1040 Delayed‐Release Hydrogel for the Treatment of Tendon Adhesion.Advanced Functional Materials.2024: 2314731. 2. Wu K, Yang B, Chen R, et al.Lack of signal peptide in insect prophenoloxidase to avoid glycosylation to damage the zymogen activity.Developmental & Comparative Immunology.2024: 105230.

References

– Sebolt-Leopold JS, et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med. 1999 Jul;5(7):810-6.

CAS Number

– 212631-79-3

Molecular Weight

– C17H14ClF2IN2O2

Compound Purity

– 0.991

SMILES

– Fc1ccc(C(=O)NOCC2CC2)c(Nc2ccc(I)cc2Cl)c1F

Pathway

– Apoptosis|||MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.