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Capsazepine

SKU T7177-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 77 CAD through 603 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Capsazepine is an antagonist of TRPV1 receptor ( IC50: 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is therefore considered to be a capsaicin antagonist.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7177

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H21ClN2O2S

Citations

– 1. Lu J, Zhou W, Dou F, et al. TRPV1 sustains microglial metabolic reprogramming in Alzheimer’s disease. EMBO reports. 2021, 22(6): e52013.

References

– Yang MH, Jung SH, Sethi G,et al.Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases[J].Molecules. 2019 Mar 12;24(5). pii: E995.

CAS Number

– 138977-28-3

Molecular Weight

– C19H21ClN2O2S

Compound Purity

– 0.9964

SMILES

– Oc1cc2CCCN(Cc2cc1O)C(=S)NCCc1ccc(Cl)cc1

Pathway

– Apoptosis|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.