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Brevilin A

SKU T4672-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 155 CAD through 3,888 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K/AKT/mTOR inactivation in colon adenocarcinoma cell CT26.antitumour

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T4672

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H26O5

References

– Antiprotozoal activities of Centipeda minima. Phytother. Res., 1994, 8(8):436-8.

CAS Number

– 16503-32-5

Molecular Weight

– C20H26O5

Compound Purity

– 0.9974

SMILES

– [H][C@@]12C[C@@H](C)[C@]3([H])C=CC(=O)[C@@]3(C)[C@@H](OC(=O)C(C)=C/C)[C@]1([H])[C@H](C)C(=O)O2

Pathway

– Microbiology/Virology|||Stem Cells|||Chromatin/Epigenetic|||Angiogenesis|||JAK/STAT signaling|||Apoptosis|||Tyrosine Kinase/Adaptors|||Autophagy

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.