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Products Details
Product Description
– BRD4-BD1-IN-2 is a selective BRD4-BD1 inhibitor, with an IC50 of 2.51 µM (20-times greater than that of BD2). BRD4-BD1-IN-2 can be used in studies of cancer and cardiovascular diseases[1].
Web ID
– HY-143300
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H15Br3N4O2
References
– [1]Chang Y, et al. Design, synthesis, biological evaluation, and molecular docking of 1, 7-dibenzyl-substituted theophylline derivatives as novel BRD4-BD1-selective inhibitors. Medicinal Chemistry Research, 2021, 30(8): 1453-1468.
CAS Number
– 2761321-26-8
Molecular Weight
– 583.07
SMILES
– CN1C(N(C(C2=C1N=C(N2CC3=CC=C(C=C3)Br)Br)=O)CC4=CC=C(C=C4)Br)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
