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Blebbistatin
$88 – $495
Products Details
Product Description
– Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor, promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, and better preserves cell junctional integrity and barrier function. Blebbistatin blocks cell migration[1][2].
Web ID
– HY-13813
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Molecular Formula
– C18H16N2O2
References
– [1]Liang Ma, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015 Jan;25(1):24-38.|[2]Ho WT, et al. Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. J Mol Med (Berl). 2019 Sep;97(9):1345-1357.
CAS Number
– 674289-55-5
Molecular Weight
– 292.33
Compound Purity
– 99.64
SMILES
– O=C1C2(O)C(N(C3=CC=CC=C3)CC2)=NC4=C1C=C(C)C=C4
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 25 mg/mL (ultrasonic)
Target
– Myosin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
