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Bis-ANS dipotassium

SKU T36956-1 mg Category Dye-Reagents Brand: TargetMol

685 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.[1] Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.[2] bis-ANS has an excitation maxima of 390 nm.[3] It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima of 484-496 nm. bis-ANS has been used to label mechanically damaged neurons in acute brain slices.4 It also potently inhibits microtubule assembly.[5],[6]

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T36956

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H22K2N2O6S2

References

– Hawe, A., Sutter, M., and Jiskoot, W. Extrinsic fluorescent dyes as tools for protein characterization. Pharm. Res. 25(7), 1487-1499 (2008).

CAS Number

– 65664-81-5

Molecular Weight

– C32H22K2N2O6S2

SMILES

– [K].[K].OS(=O)(=O)c1cccc2c(ccc(Nc3ccccc3)c12)-c1ccc(Nc2ccccc2)c2c(cccc12)S(O)(=O)=O

Product type

– Dye-Reagents

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.