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Bevantolol (hydrochloride)
$28 – $217
Products Details
Product Description
– Bevantolol hydrochloride is a selective β1 and α1-adrenergic receptor antagonist with pKi values of 7.83, 6.9 in rat cerebral cortex, respectively. Bevantolol hydrochloride is a potent Ca2+ antagonist[1][2].
Web ID
– HY-121186
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C20H28ClNO4
References
– [1]Takahiro Horinouchi, et al. Different Changes of Plasma Membrane Beta-Adrenoceptors in Rat Heart After Chronic Administration of Propranolol, Atenolol and Bevantolol. Life Sci. 2007 Jul 12;81(5):399-404.|[2]M Takita, et al. Selectivity of Bevantolol Hydrochloride Towards Alpha- And Beta-Adrenoceptor Subtypes in Rat Cerebral Cortex. Jpn J Pharmacol. 1992 Feb;58(2):193-6.
CAS Number
– 42864-78-8
Molecular Weight
– 381.89
Compound Purity
– 98.98
SMILES
– OC(CNCCC1=CC=C(C(OC)=C1)OC)COC2=CC=CC(C)=C2.[H]Cl
Clinical Information
– Launched
Research Area
– Metabolic Disease; Neurological Disease
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)|H2O : 4.55 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Adrenergic Receptor;Calcium Channel
Isoform
– α adrenergic receptor;β adrenergic receptor
Pathway
– GPCR/G Protein;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
