Download Files:

Bestatin

SKU T1257-5 mg Category Natural Product Brand: TargetMol

Price range: 77 CAD through 1,165 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

Clear

Products Details

Product Description

– Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Aminopeptidases has been implicated in the process of cell adhesion and invasion of tumor cells. Therefore, inhibiting aminopeptidases may partially attribute to the antitumor effect of ubenimex. This agent also activates T lymphocyte, macrophage, and bone marrow stem cell as well as stimulates the release of interleukin-1 and -2, thus further enhances its antitumor activity.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T1257

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H24N2O4

Citations

– 1. Jiang T Y, Pan Y F, Wan Z H, et al. PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma. Science Translational Medicine. 2020, 12(562). 2. Jiang T Y, Feng X F, Fang Z, et al. PTEN deficiency facilitates the therapeutic vulnerability to proteasome inhibitor bortezomib in gallbladder cancer. Cancer Letters. 2021, 501: 187-199.

References

– Sekine K, et al. Leukemia, 1999, 13(5), 729-734.

CAS Number

– 58970-76-6

Molecular Weight

– C16H24N2O4

Compound Purity

– 0.9935

SMILES

– C([C@H]([C@@H](C(N[C@@H](CC(C)C)C(O)=O)=O)O)N)C1=CC=CC=C1

Target

– Sodium Channel

Pathway

– Immunology/Inflammation|||Microbiology/Virology|||Metabolism

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.