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AZ960

SKU T6309-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 107 CAD through 909 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

2 mg 1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6309

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16F2N6

Citations

– 1. Chen C, Lu M, Lin S, et al. The nuclear gene rpl18 regulates erythroid maturation via JAK2-STAT3 signaling in zebrafish model of Diamond–Blackfan anemia. Cell Death & Disease. 2020, 11(2): 1-11

References

– Gozgit JM, et al. J Biol Chem. 2008, 283(47), 32334-32343.

CAS Number

– 905586-69-8

Molecular Weight

– C18H16F2N6

Compound Purity

– 0.9851

SMILES

– C[C@H](Nc1nc(Nc2cc(C)[nH]n2)c(F)cc1C#N)c1ccc(F)cc1

Pathway

– JAK/STAT signaling|||Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||Microbiology/Virology|||Stem Cells|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.