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AZ-Dyrk1B-33

$200$1,790

Products Details

Product Description

– AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].

Web ID

– HY-117391

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C19H16N4

References

– [1]Kettle JG, et al. Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. J Med Chem. 2015 Mar 26;58(6):2834-44.

CAS Number

– 1679330-37-0

Molecular Weight

– 300.36

Compound Purity

– 99.95

SMILES

– CC1=NC=CC(C2=CN(CC3=CC=CC=C3)C4=C2C=CN=C4)=N1

Clinical Information

– No Development Reported

Research Area

– Cancer; Metabolic Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– DYRK

Isoform

– DYRK1

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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