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AZ-3
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T10424
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H28FN7
References
– Grimster NP, et al. Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors. J Med Chem. 2018 Jun 28;61(12):5235-5244.
CAS Number
– 2228908-91-4
Molecular Weight
– C20H28FN7
SMILES
– CN1C[C@]2(N(C[C@@]1(C2)[H])C=3C=C(NC=4N=C(N[C@@H](CC)C)C(C)=CN4)C(F)=NC3)[H]
Target
– Others
Pathway
– Angiogenesis|||Stem Cells|||Chromatin/Epigenetic|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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