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AWD 12-281

SKU T30232-1 mg Category Small Compound Brand: TargetMol

Price range: 469 CAD through 3,168 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory and bronchodilator activity used in the study of chronic obstructive pulmonary disease (COPD).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T30232

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H14Cl2FN3O3

References

– Hoppmann J,et al. The phosphodiesterase 4 inhibitor AWD 12-281 is active in a new guinea-pig model of allergic skin inflammation predictive of human skin penetration and suppresses both Th1 and Th2 cytokines in mice. J Pharm Pharmacol. 2005 Dec;57(12):1609-17. PubMed PMID: 16354405.

CAS Number

– 257892-33-4

Molecular Weight

– C22H14Cl2FN3O3

Compound Purity

– 0.9985

SMILES

– O=C(NC=1C(Cl)=CN=CC1Cl)C(=O)C2=CN(C=3C=CC(O)=CC23)CC4=CC=C(F)C=C4

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.