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Aumitin

SKU T14346-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 94 CAD through 1,728 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Aumitin, a diaminopyrimidine-based autophagy inhibitor, dose-dependently inhibits starvation- and rapamycin-induced autophagy with IC50s of 0.12 μM and 0.24 μM, respectively [1], and also inhibits mitochondrial respiration by targeting complex I.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T14346

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H20ClN5O

References

– Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.

CAS Number

– 946293-78-3

Molecular Weight

– C24H20ClN5O

Compound Purity

– 0.9913

SMILES

– Cc1cc(Nc2ccccc2)nc(Nc2ccc(NC(=O)c3ccccc3Cl)cc2)n1

Target

– Others

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.