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ATM Inhibitor-11
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– ATMInhibitor-11 (Compound 1) is an inhibitor of ATM with an IC50 of 0.32 nM. It also inhibits KAP1 phosphorylation with an IC50 of 0.97 nM. This compound exhibits high exposure in the brain, heart, and plasma of ICR mice. Furthermore, ATMInhibitor-11 demonstrates antitumor activity in the NCI-H441 xenograft mouse model.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T201457
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C27H33FN6O2
CAS Number
– 2878473-51-7
Molecular Weight
– C27H33FN6O2
SMILES
– O=C1N(C=2C=NC=3C=C(F)C(=CC3C2N1C(C)C)C=4C=NC(OCCCN5CCN(C)CC5)=CC4)C
Target
– Akt
Pathway
– DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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