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ATG7-IN-1

SKU T39705-1 mg Category Small Compound Brand: TargetMol

Price range: 526 CAD through 4,688 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

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Products Details

Product Description

– ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T39705

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H19FN6O5S2

Citations

– 1. Zhang W, Chen L, Liu J, et al.Inhibition of autophagy-related protein 7 enhances anti-tumor immune response and improves efficacy of immune checkpoint blockade in microsatellite instability colorectal cancer.Journal of Experimental & Clinical Cancer Research.2024, 43(1): 1-19.

References

– Huang SC, et al. Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors. Bioorg Med Chem. 2020 Oct 1;28(19):115681.

CAS Number

– 2226229-87-2

Molecular Weight

– C17H19FN6O5S2

Compound Purity

– 1

SMILES

– S(C=1C=2C(N(N1)[C@@H]3O[C@@H](COS(N)(=O)=O)[C@@H](O)C3)=NC=NC2N)C4=C(F)C=C(C)C=C4

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.