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ATC 0175 hydrochloride

SKU T22591-1 mg Category Small Compound Brand: TargetMol

Price range: 115 CAD through 4,784 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM, >10,000 nM, 13 nM, 9.66 nM and 16.9 nM, respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T22591

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H26ClF2N5O

References

– Semple G, et al. Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175: in vitro profiling and in vivo evaluation. Bioorg Med Chem Lett. 2009 ; 19(21):6166-6171.

CAS Number

– 510733-97-8

Molecular Weight

– C23H26ClF2N5O

Compound Purity

– 0.9984

SMILES

– N(C)(C)C=1C2=C(N=C(N[C@H]3CC[C@@H](NC(=O)C4=CC(F)=C(F)C=C4)CC3)N1)C=CC=C2.Cl

Pathway

– Neuroscience|||Endocrinology/Hormones|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.