AS1810722

SKU T9043-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 170 CAD through 1,427 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– AS1810722, a fused bicyclic pyrimidine derivative, is an orally active and potent inhibitor of STAT6, demonstrating an IC50 of 1.9 nM. It exhibits effective inhibition of CYP3A4, positioning it as a promising candidate for research into allergic diseases, including asthma and atopic conditions.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T9043

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H25F2N7O

References

– Nagashima S , Hondo T , Nagata H , et al. Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors[J]. Bioorg Med Chem, 2009, 17(19):6926-6936.

CAS Number

– 909561-15-5

Molecular Weight

– C25H25F2N7O

Compound Purity

– 0.9913

SMILES

– NC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1

Pathway

– JAK/STAT signaling|||Metabolism|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Proudly representing

150+ years of combined research-supply heritage

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.