Artesunate

SKU T0433-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 299 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection. It is on the World Health Organization’s List of Essential Medicines.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T0433

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H28O8

Citations

– 1. Liu Y, Li H, Luo Z, et al. Artesunate, a new antimalarial clinical drug, exhibits potent anti‐AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways. British Journal of Pharmacology. 2022 2. Jin J, Guo D, Wang Y, et al. Artesunate Inhibits the Development of Esophageal Cancer by Targeting HK1 to Reduce Glycolysis Levels in Areas With Zinc Deficiency. Frontiers in Oncology. 2022: 1956 3. Bowden G D, Land K M, O’Connor R M, et al. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth. International Journal for Parasitology: Drugs and Drug Resistance. 2018 Apr;8(1): 137-144 4. Wang J, Zhang J, Guo Z, et al.Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.Phytomedicine.2023: 155156. 5. Han X, Jiang S, Hu C, et al.Inhibition of Keloid Fibroblast Proliferation by Artesunate is Mediated by Targeting the IRE1α/XBP1 Signaling Pathway and Decreasing TGF-β1.Burns.2024

References

– Xu N, et al. Int J Med Sci. 2015, 12(6):524-529.

CAS Number

– 88495-63-0

Molecular Weight

– C19H28O8

Compound Purity

– 0.9991

SMILES

– C[C@@H]1[C@]2([C@]34[C@](O[C@H]1OC(CCC(O)=O)=O)(O[C@](C)(OO3)CC[C@]4([C@H](C)CC2)[H])[H])[H]

Target

– ADC Cytotoxin

Pathway

– Apoptosis|||Stem Cells|||JAK/STAT signaling|||Microbiology/Virology

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.