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ARS-853

SKU T7414-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 245 CAD through 5,488 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– ARS-853 is an inhibitor of K-RASG12C(IC50: 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7414

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H29ClN4O3

References

– Lito P , Solomon M , Li L S , et al. Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism[J]. Science, 2016:science.aad6204.

CAS Number

– 1629268-00-3

Molecular Weight

– C22H29ClN4O3

Compound Purity

– 0.984

SMILES

– CC1(CC1)c1cc(NCC(=O)N2CCN(CC2)C2CN(C2)C(=O)C=C)c(O)cc1Cl

Pathway

– MAPK|||Apoptosis|||GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.