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ARB-272572

SKU T39914-1 mg Category Small Compound Brand: TargetMol

Price range: 222 CAD through 3,552 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– ARB-272572 is a potent inhibitor of programmed cell death ligand 1 (PD-L1) signaling that induces PD-L1 homodimer interactions and produces immunostimulatory activity in human primary cells.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T39914

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H36N6O4

References

– Park JJ, et al. Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun. 2021 Feb 22;12(1):1222.

CAS Number

– 2368182-63-0

Molecular Weight

– C32H36N6O4

Compound Purity

– 0.9807

SMILES

– O=C(NC1=CC=CC(C=2C=CC=C(NC(=O)C3=NC=C(C=C3)CNCCO)C2C)=C1C)C4=NC=C(C=C4)CNCCO

Pathway

– Apoptosis|||Immunology/Inflammation|||Cell Cycle/Checkpoint

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.