AP 18
Add to CompareAdded to Compare

Download Files:

AP 18

SKU T21543-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 67 CAD through 795 CAD

Products Details

Product Description

– AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 could reverse complete Freund’s adjuvant (CFA)-induced mechanical hyperalgesia in mice. AP-18 could attenuate Yo-Pro uptake induced by 30 μM AITC in a concentration-dependent manner (IC50= 10.3 μM).

Web ID

– T21543

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C11H12ClNO

References

– Matt Petrus, et al. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain. 2007;3:40. Published 2007 Dec 17.

CAS Number

– 55224-94-7

Molecular Weight

– C11H12ClNO

Compound Purity

– 0.9987

SMILES

– CC(=C/c1ccc(Cl)cc1)C(C)=NO

Target

– Kras

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Mexenone
Mexenone Price range: 48 CAD through 157 CAD
1 mL * 10 mM (in DMSO)100 mg200 mg

1000 in stock

Select options
6-Mercaptopurine
6-Mercaptopurine Price range: 50 CAD through 190 CAD
1 g1 mL * 10 mM (in DMSO)25 mg

1000 in stock

Select options
Sodium Nitroprusside
Sodium Nitroprusside Price range: 64 CAD through 139 CAD
1 mL * 10 mM (in DMSO)100 mg50 mg

1000 in stock

Read more
(R)-(+)-Atenolol
(R)-(+)-Atenolol
Add to cart
4-(Imidazol-1-yl)phenol
4-(Imidazol-1-yl)phenol 46 CAD

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });