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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthesis and renal activity in humans.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T7040
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C50H71N13O12
Citations
– 1. Zhang R Y, Wu C M, Hu X M, et al. LncRNA AC105942. 1 Downregulates hnRNPA2/B1 to Attenuate Vascular Smooth Muscle Cells Proliferation. DNA and Cell Biology. 2021
2. Zhang L, Zhang B, Yu Y, et al. Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload. International Heart Journal. 2021: 20-384
3. Li J, Wei L, Hu K, et al.Deciphering m6A methylation in monocyte-mediated cardiac fibrosis and monocyte-hitchhiked erythrocyte microvesicle biohybrid therapy.Theranostics.2024, 14(9): 3486.
4. Guo X, Chen Z, Gao C, et al.20S-O-Glc-DM treats metabolic syndrome-induced heart failure through regulating gut flora.European Journal of Pharmacology.2024, 982: 176946.
References
– Ji Y, et al. Angiotensin II Enhances Proliferation and Inflammation through AT1/PKC/NF-κB Signaling Pathway in Hepatocellular Carcinoma Cells. Cell Physiol Biochem. 2016 Jul;39(1):13-32.
CAS Number
– 4474-91-3
Molecular Weight
– C50H71N13O12
Compound Purity
– 0.9987
SMILES
– CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(O)=O
Pathway
– Apoptosis|||Endocrinology/Hormones
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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