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anemarsaponin B

SKU T7030-1 mL * 10 mM (in DMSO) Category Natural Product Brand: TargetMol

Price range: 134 CAD through 1,157 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activity, possibly via the p38 MAP kinase pathway. Anemarsaponin B can inhibit PAF-induced rabbit platelet aggregation in vitro.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T7030

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C45H74O18

References

– Kim J Y, et al. Anti-inflammatory effect of anemarsaponin B isolated from the rhizomes of Anemarrhena asphodeloides in LPS-induced RAW 264.7 macrophages is mediated by negative regulation of the nuclear factor-kappaB and p38 pathways.[J]. Food & Chemical Toxicology, 2009, 47(7):1610-1617.

CAS Number

– 139051-27-7

Molecular Weight

– C45H74O18

Compound Purity

– 0.9981

SMILES

– CC12C(C3C(CC1)C4(C)C(CC3)CC(OC5C(OC6OC(CO)C(O)C(O)C6O)C(O)C(O)C(CO)O5)CC4)CC7C2C(C)=C(CCC(COC8OC(CO)C(O)C(O)C8O)C)O7

Pathway

– Neuroscience|||Immunology/Inflammation|||MAPK|||NF-κB

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.