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Products Details
Product Description
– Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria[1][2].
Web ID
– HY-107813
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H43N5O13.9/5H2O4S
References
Р[1]Edson, R.S. and C.L. Terrell, The aminoglycosides. Mayo Clin Proc, 1999. 74(5): p. 519-28.|[2]Ristuccia AM, et al. An overview of amikacin. Ther Drug Monit. 1985;7(1):12-25.|[3]Si̢n R Kitcher, et al. ORC-13661 Protects Sensory Hair Cells From Aminoglycoside and Cisplatin Ototoxicity. JCI Insight. 2019 Aug 8;4(15):e126764.
CAS Number
– 149022-22-0
Molecular Weight
– 762.14
SMILES
– O[C@@H]1[C@H]([C@@H](C[C@H](N)[C@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)O)([H])O[C@@H]2CN)NC([C@@H](O)CCN)=O)O[C@@]([C@@H]([C@@H](N)[C@@H]3O)O)([H])O[C@@H]3CO.O=[S](O)(O)=O.[9/5]
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Isoform
– Aminoglycoside
Pathway
– Anti-infection
Product type
– Reference compound
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