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AMG-369

SKU T29971-1 mg Category Small Compound Brand: TargetMol

Price range: 661 CAD through 3,136 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

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Products Details

Product Description

– AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the onset of experimental autoimmune encephalomyelitis in rats. encephalomyelitis in rats.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T29971

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H22FN3O2S

References

– Victor J. Cee*†, Mike Frohn†, Brian A. Lanman†, Jennifer Golden†, Kristine Muller†, Susana Neira†, Alex Pickrell†, Heather Arnett‡, Janet Buys†, Anu Gore†, Mike Fiorino†, Michelle Horner†, Andrea Itano†, Matt R. Lee†, Michele McElvain†, Scot Middleton†, Michael Schrag†, Dalia Rivenzon-Segal§, Hugo M. Vargas†, Han Xu†, Yang Xu†, Xuxia Zhang†, Jerry Siu†, Min Wong†, and Roland W. Bürli. Discovery of AMG 369, a Thiazolo[5,4-b]pyridine Agonist of S1P1 and S1P5. ACS Med. Chem. Lett., 2011, 2 (2), pp 107–112

CAS Number

– 1202073-26-4

Molecular Weight

– C26H22FN3O2S

Compound Purity

– 0.9892

SMILES

– O=C(O)C1CN(CC2=CC=C(C(F)=C2)C3=NC=4C=CC(=NC4S3)C5(C=6C=CC=CC6)CC5)C1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.