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Products Details
Product Description
– Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase[1].
Web ID
– HY-115194
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H39ClN4O8
References
– [1]S H Wilkes, et al. The Slow, Tight Binding of Bestatin and Amastatin to Aminopeptidases. J Biol Chem. 1985 Oct 25;260(24):13154-62.|[2]J J Millership, et al. In Vitro and in Vivo Evaluation of Aminopeptidase Inhibitors as Antimicrosporidial Therapies. J Eukaryot Microbiol. 2001;Suppl:95S-98S.
CAS Number
– 100938-10-1
Molecular Weight
– 511.01
SMILES
– O=C(O)C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@@H](O)[C@H](N)CC(C)C)=O)=O)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Aminopeptidase;Bacterial
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
