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Alvespimycin hydrochloride

SKU T6297-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 54 CAD through 277 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 25 mg 5 mg 50 mg

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Products Details

Product Description

– Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6297

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H48N4O8·HCl

Citations

– 1. Lin H Y H, Chen I Y, Wang T M, et al.Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome.Kidney International Reports.2024 2. The Role of Mitochondrial AKT1 Signaling in Renal Tubular Injury of Metabolic Syndrome

References

– Ge J, et al. J Med Chem, 2006, 49(15), 4606-4615.

CAS Number

– 467214-21-7

Molecular Weight

– C32H48N4O8·HCl

Compound Purity

– 0.9994

SMILES

– Cl.COC1CC(C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)C(C)=CC=CC(OC)C(OC(N)=O)C(C)=CC(C)C1O)C2=O

Pathway

– Cytoskeletal Signaling|||Metabolism|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.