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Alantolactone
80 CAD – 672 CADPrice range: 80 CAD through 672 CAD
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T2896
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H20O2
Citations
– 1. Hu Y, Wen Q, Cai Y, et al.Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.Phytomedicine.2023, 108: 154528.
2. Liu Y, Guo Y, Zeng Q, et al.Prosapogenin A induces GSDME-dependent pyroptosis of anaplastic thyroid cancer through vacuolar ATPase activation-mediated lysosomal over-acidification.Cell Death & Disease.2024, 15(8): 586.
References
– Chun J, et al. Cancer Lett. 2015, 357(1):393-403.
CAS Number
– 546-43-0
Molecular Weight
– C15H20O2
Compound Purity
– 0.9991
SMILES
– [H][C@@]12C[C@@]3(C)CCC[C@H](C)C3=C[C@]1([H])C(=C)C(=O)O2
Pathway
– JAK/STAT signaling|||Stem Cells|||Apoptosis
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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