Alantolactone

SKU T2896-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 80 CAD through 672 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Products Details

Product Description

– Alantolactone is a selective inhibitor of STAT3 that induces cancer-associated apoptosis and has antitumor activity.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T2896

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H20O2

Citations

– 1. Hu Y, Wen Q, Cai Y, et al.Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.Phytomedicine.2023, 108: 154528. 2. Liu Y, Guo Y, Zeng Q, et al.Prosapogenin A induces GSDME-dependent pyroptosis of anaplastic thyroid cancer through vacuolar ATPase activation-mediated lysosomal over-acidification.Cell Death & Disease.2024, 15(8): 586.

References

– Chun J, et al. Cancer Lett. 2015, 357(1):393-403.

CAS Number

– 546-43-0

Molecular Weight

– C15H20O2

Compound Purity

– 0.9991

SMILES

– [H][C@@]12C[C@@]3(C)CCC[C@H](C)C3=C[C@]1([H])C(=C)C(=O)O2

Pathway

– JAK/STAT signaling|||Stem Cells|||Apoptosis

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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For Research Use Only. All Immunomart products are sold strictly for laboratory research use only (RUO). Not for human or veterinary consumption, therapeutic, or diagnostic use.