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Products Details
Product Description
– Ala-Ala-Asn-PAB is a peptide cleavable ADC linker for antibody-drug conjugates (ADCs)[1].
Web ID
– HY-129360
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H25N5O5
References
– [1]Cheng X, et al. MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity. Mol Cancer Ther. 2018 Dec;17(12):2665-2675.
CAS Number
– 2149584-00-7
Molecular Weight
– 379.41
SMILES
– OCC1=CC=C(NC([C@H](CC(N)=O)NC([C@H](C)NC([C@@H](N)C)=O)=O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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