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AK301

SKU T26585-1 mg Category Small Compound Brand: TargetMol

Price range: 336 CAD through 1,525 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

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Products Details

Product Description

– AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T26585

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H21ClN2O2

References

– Chopra A, et al. Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK30PLoS One. 2016 Apr 20;11(4):e0153818.

CAS Number

– 314022-97-4

Molecular Weight

– C19H21ClN2O2

Compound Purity

– 0.9945

SMILES

– C(=O)(C1=C(OCC)C=CC=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3

Pathway

– Apoptosis|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.