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AJI-214

SKU T200387-25 mg Category Small Compound Brand: TargetMol

Price range: 2,432 CAD through 4,000 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

100 mg 25 mg 50 mg

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Products Details

Product Description

– AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T200387

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H13ClFN5O

CAS Number

– 1395886-20-0

Molecular Weight

– C17H13ClFN5O

SMILES

– O=C(N)C1=CC=C(C=C1)NC2=NC=C(F)C(=N2)NC=3C=CC=CC3Cl

Target

– Acetyl-CoA Carboxylase

Pathway

– Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint|||Stem Cells|||JAK/STAT signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.