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Products Details
Product Description
– AG 1406 (compound M19) is a HER2 inhibitor, with an IC50 of 10.57 μM for HER2 in BT474 cell and >50 μM for EGFR in EGF-3T3 cell[1].
Web ID
– HY-108931
Shipping
– Room temperature
Molecular Formula
– C16H18N2O
References
– [1]Hui Chen, et al. Methods and compositions for inhibiting cell proliferative disorders. Patent, US5789427A.
CAS Number
– 71308-34-4
Molecular Weight
– 254.33
SMILES
– N#C/C(C#N)=C/C1=CC(C(C)C)=C(O)C(C(C)C)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– EGFR
Pathway
– JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
