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ADH-1 (trifluoroacetate)
$132 – $900
Products Details
Product Description
– ADH-1 trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion.
Web ID
– HY-13541A
Storage Temperature
– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H35F3N8O8S2
References
– [1]Li H, et al. ADH1, an N-cadherin inhibitor, evaluated in preclinical models of angiogenesis and androgen-independent prostate cancer. Anticancer Drugs. 2007 Jun;18(5):563-8.|[2]Turley RS, et al. Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma. Ann Surg. 2015 Feb;261(2):368-77|[3]Shintani Y, et al. ADH-1 suppresses N-cadherin-dependent pancreatic cancer progression. Int J Cancer. 2008 Jan 1;122(1):71-7.
CAS Number
– 1135237-88-5
Molecular Weight
– 684.71
Compound Purity
– 99.74
SMILES
– O=C([C@@H](NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CC1=CN=CN1)N2)=O)=O)=O)CSSC[C@H](NC(C)=O)C2=O)N.O=C(O)C(F)(F)F
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : ≥ 43 mg/mL|H2O : 33.33 mg/mL (ultrasonic)
Target
– Others
Pathway
– Others
Product type
– Peptides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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