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ABT-418 (hydrochloride)
$120 – $850
Products Details
Product Description
– ABT-418 hydrochloride is a potent and selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. ABT-418 hydrochloride activates cholinergic channel and can be used for research of Alzheimer’s disease[1][2].
Web ID
– HY-105170B
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C9H15ClN2O
References
– [1]Brioni JD, et al. Anxiolytic-like effects of the novel cholinergic channel activator ABT-418. J Pharmacol Exp Ther. 1994 Oct;271(1):353-61.|[2]Guo T, et al. A comparative study of the effects of ABT-418 and methylphenidate on spatial memory in an animal model of ADHD. Neurosci Lett. 2012 Oct 18;528(1):11-5.
CAS Number
– 147388-83-8
Molecular Weight
– 202.68
Compound Purity
– 99.37
SMILES
– CN1[C@H](C2=CC(C)=NO2)CCC1.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 11.9 mg/mL (ultrasonic)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
