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For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T4515
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H22ClN3O3
Citations
– 1. Liu Y, Wang Y, Lin Z, et al.SLC25A22 as a key mitochondrial transporter against ferroptosis by producing GSH and MUFAs.Antioxidants and Redox Signaling.2023 (ja).
2. Huang F, Zhao N, Cai P, et al.Active AKT2 stimulation of SREBP1/SCD1-mediated lipid metabolism boosts hepatosteatosis and cancer.Translational Research.2024
References
– Roongta U V , Pabalan J G , Wang X , et al. Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy[J]. Molecular Cancer Research, 2011, 9(11):1551-1561.
CAS Number
– 1032229-33-6
Molecular Weight
– C20H22ClN3O3
Compound Purity
– 0.9996
SMILES
– CNC(=O)c1cccc(NC(=O)N2CCC(CC2)Oc2ccccc2Cl)c1
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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