Download Files:

A 922500

SKU T6365-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 69 CAD through 1,413 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mg 1 mL * 10 mM (in DMSO)10 mg 100 mg 200 mg 25 mg 5 mg 50 mg

Clear

Products Details

Product Description

– A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor of human and mouse DGAT-1 with IC50 values of 7 nM and 24 nM, respectively, demonstrating good selectivity over related acyltransferases, hERG, and a panel of anti-targets.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T6365

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C26H24N2O4

Citations

– 1. Masouleh S K. Lipid droplet formation drives pathogenic ILC2 responses in airway inflammation. Immunity. 2020 2. Karagiannis F, Masouleh S K, Wunderling K, et al. Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation. Immunity. 2020, 52(4): 620-634. e6. 3. Wang W, Qu Y, Wang X, et al.Genetic variety of ORF3a shapes SARS‐CoV‐2 fitness through modulation of lipid droplet.Journal of Medical Virology.2023

References

– King AJ et al. J Pharmacol Exp Ther. 2009, 330(2), 526-531.

CAS Number

– 959122-11-3

Molecular Weight

– C26H24N2O4

Compound Purity

– 0.9766

SMILES

– OC(=O)[C@@H]1CCC[C@H]1C(=O)c1ccc(cc1)-c1ccc(NC(=O)Nc2ccccc2)cc1

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.